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Hepatitis E virus persists in the presence of a type III interferon response

The RIG-I-like RNA helicase (RLR)-mediated interferon (IFN) response plays a pivotal role in the hepatic antiviral immunity. The hepatitis A virus (HAV) and the hepatitis C virus (HCV) counter this response by encoding a viral protease that cleaves the mitochondria antiviral signaling protein (MAVS)...

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Detalles Bibliográficos
Autores principales: Yin, Xin, Li, Xinlei, Ambardekar, Charuta, Hu, Zhimin, Lhomme, Sébastien, Feng, Zongdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466342/
https://www.ncbi.nlm.nih.gov/pubmed/28558073
http://dx.doi.org/10.1371/journal.ppat.1006417