Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging

TAR DNA-binding protein 43 (TDP-43) is a main constituent of cytoplasmic aggregates in neuronal and glial cells in cases of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. We have previously demonstrated that adenovirus-transduced artificial TDP-43 cytoplasmic aggregates formati...

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Detalles Bibliográficos
Autores principales: Ishii, Tomohiro, Kawakami, Emiko, Endo, Kentaro, Misawa, Hidemi, Watabe, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466347/
https://www.ncbi.nlm.nih.gov/pubmed/28599005
http://dx.doi.org/10.1371/journal.pone.0179375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466347/
https://www.ncbi.nlm.nih.gov/pubmed/28599005
http://dx.doi.org/10.1371/journal.pone.0179375

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