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Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging

TAR DNA-binding protein 43 (TDP-43) is a main constituent of cytoplasmic aggregates in neuronal and glial cells in cases of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. We have previously demonstrated that adenovirus-transduced artificial TDP-43 cytoplasmic aggregates formati...

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Detalles Bibliográficos
Autores principales:	Ishii, Tomohiro, Kawakami, Emiko, Endo, Kentaro, Misawa, Hidemi, Watabe, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466347/ https://www.ncbi.nlm.nih.gov/pubmed/28599005 http://dx.doi.org/10.1371/journal.pone.0179375

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