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A comprehensive overview and evaluation of circular RNA detection tools

Circular RNA (circRNA) is mainly generated by the splice donor of a downstream exon joining to an upstream splice acceptor, a phenomenon known as backsplicing. It has been reported that circRNA can function as microRNA (miRNA) sponges, transcriptional regulators, or potential biomarkers. The availab...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangxiang, Lin, Wei, Guo, Maozu, Zou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466358/
https://www.ncbi.nlm.nih.gov/pubmed/28594838
http://dx.doi.org/10.1371/journal.pcbi.1005420