A humanized HLA-DR4 mouse model for autoimmune myocarditis

Myocarditis, the principal cause of dilated cardiomyopathy and heart failure in young adults, is associated with autoimmunity to human cardiac α-myosin (hCAM) and the DR4 allele of human major histocompatibility II (MHCII). We developed an hCAM-induced myocarditis model in human HLA-DR4 transgenic m...

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Detalles Bibliográficos
Autores principales: Şelli, M. Emrah, Thomas, Anita C., Wraith, David C., Newby, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466360/
https://www.ncbi.nlm.nih.gov/pubmed/28431892
http://dx.doi.org/10.1016/j.yjmcc.2017.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466360/
https://www.ncbi.nlm.nih.gov/pubmed/28431892
http://dx.doi.org/10.1016/j.yjmcc.2017.04.003

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