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Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells

S100A8/A9, a heterodimer of the two calcium-binding proteins S100A8 and S100A9, has emerged as an important proinflammatory mediator in acute and chronic inflammation. However, whether S100A8/A9 is implicated in microglial-induced neuroinflammatory response remains unclear. Here, we found that S100A...

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Detalles Bibliográficos
Autores principales: Ma, Li, Sun, Peng, Zhang, Jian-Cheng, Zhang, Qing, Yao, Shang-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466387/
https://www.ncbi.nlm.nih.gov/pubmed/28498464
http://dx.doi.org/10.3892/ijmm.2017.2987