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hsa-miR-485-5p reverses epithelial to mesenchymal transition and promotes cisplatin-induced cell death by targeting PAK1 in oral tongue squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is currently a highly prevalent disease worldwide. Cisplatin (CDDP) is widely used for the chemotherapy of OSCC. Yet, the molecular mechanisms responsible for cisplatin resistance have not been fully elucidated. In this study, we showed that overexpression of p21...

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Detalles Bibliográficos
Autores principales: Lin, Xiu-Juan, He, Chang-Li, Sun, Ting, Duan, Xue-Jing, Sun, Yi, Xiong, Shi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466395/
https://www.ncbi.nlm.nih.gov/pubmed/28535002
http://dx.doi.org/10.3892/ijmm.2017.2992