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FoxO3a plays a key role in the protective effects of pomegranate peel extract against amikacin-induced ototoxicity

The use of amikacin (AMK) in present treatment strategies results in severe ototoxicity; however, the underlying molecular mechanisms of this toxicity remain unclear. In this study, we investigated the effectiveness of orally administered pomegranate peel extract (PPE), a strong antioxidant, as a pr...

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Detalles Bibliográficos
Autores principales: Liu, Shuangyue, Zhang, Xiao, Sun, Meiling, Xu, Tao, Wang, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466397/
https://www.ncbi.nlm.nih.gov/pubmed/28560451
http://dx.doi.org/10.3892/ijmm.2017.3003