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Low-Cell-Number Epigenome Profiling Aids the Study of Lens Aging and Hematopoiesis
Understanding how chromatin modification regulates development and disease can be limited by available material. Despite recent progress, balancing high-quality and reliable mapping using chromatin-immunoprecipitation-based deep sequencing (ChIP-seq) remains a challenge. We report two techniques, re...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466415/ https://www.ncbi.nlm.nih.gov/pubmed/26549448 http://dx.doi.org/10.1016/j.celrep.2015.10.004 |