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Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses

The subunit composition of synaptic NMDA receptors (NMDAR), such as the relative content of GluN2A- and GluN2B-containing receptors, greatly influences the glutamate synaptic transmission. Receptor co-agonists, glycine and D-serine, have intriguingly emerged as potential regulators of the receptor t...

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Detalles Bibliográficos
Autores principales: Ferreira, Joana S, Papouin, Thomas, Ladépêche, Laurent, Yao, Andrea, Langlais, Valentin C, Bouchet, Delphine, Dulong, Jérôme, Mothet, Jean-Pierre, Sacchi, Silvia, Pollegioni, Loredano, Paoletti, Pierre, Oliet, Stéphane Henri Richard, Groc, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466419/
https://www.ncbi.nlm.nih.gov/pubmed/28598327
http://dx.doi.org/10.7554/eLife.25492