The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland

Salivary glands, such as submandibular glands (SMGs), are composed of branched epithelial ductal networks that terminate in acini that together produce, transport and secrete saliva. Here, we show that the transcriptional regulator Yap, a key effector of the Hippo pathway, is required for the proper...

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Detalles Bibliográficos
Autores principales: Szymaniak, Aleksander D, Mi, Rongjuan, McCarthy, Shannon E, Gower, Adam C, Reynolds, Taylor L, Mingueneau, Michael, Kukuruzinska, Maria, Varelas, Xaralabos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466420/
https://www.ncbi.nlm.nih.gov/pubmed/28492365
http://dx.doi.org/10.7554/eLife.23499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466420/
https://www.ncbi.nlm.nih.gov/pubmed/28492365
http://dx.doi.org/10.7554/eLife.23499

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