Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration

Altered DNA methylation status is associated with human diseases and cancer; however, the underlying molecular mechanisms remain elusive. We previously identified many human transcription factors, including Krüppel-like factor 4 (KLF4), as sequence-specific DNA methylation readers that preferentiall...

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Detalles Bibliográficos
Autores principales: Wan, Jun, Su, Yijing, Song, Qifeng, Tung, Brian, Oyinlade, Olutobi, Liu, Sheng, Ying, Mingyao, Ming, Guo-li, Song, Hongjun, Qian, Jiang, Zhu, Heng, Xia, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466421/
https://www.ncbi.nlm.nih.gov/pubmed/28553926
http://dx.doi.org/10.7554/eLife.20068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466421/
https://www.ncbi.nlm.nih.gov/pubmed/28553926
http://dx.doi.org/10.7554/eLife.20068

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