Enforcement of developmental lineage specificity by transcription factor Oct1

Embryonic stem cells co-express Oct4 and Oct1, a related protein with similar DNA-binding specificity. To study the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and inducible-conditional Oct1-deficient ESC lines. ESCs lacking Oct1 show normal appearance, self...

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Detalles Bibliográficos
Autores principales: Shen, Zuolian, Kang, Jinsuk, Shakya, Arvind, Tabaka, Marcin, Jarboe, Elke A, Regev, Aviv, Tantin, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466424/
https://www.ncbi.nlm.nih.gov/pubmed/28537559
http://dx.doi.org/10.7554/eLife.20937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466424/
https://www.ncbi.nlm.nih.gov/pubmed/28537559
http://dx.doi.org/10.7554/eLife.20937

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