A sphingosine‐1‐phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration

BACKGROUND AND PURPOSE: Intracranial aneurysm (IA), common in the general public, causes lethal subarachnoid haemorrhage on rupture. It is, therefore, of utmost importance to prevent the IA from rupturing. However, there is currently no medical treatment. Recent studies suggest that IA is the result...

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Detalles Bibliográficos
Autores principales: Yamamoto, Rie, Aoki, Tomohiro, Koseki, Hirokazu, Fukuda, Miyuki, Hirose, Jun, Tsuji, Keiichi, Takizawa, Katsumi, Nakamura, Shinichiro, Miyata, Haruka, Hamakawa, Nozomu, Kasuya, Hidetoshi, Nozaki, Kazuhiko, Hirayama, Yoshitaka, Aramori, Ichiro, Narumiya, Shuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466536/
https://www.ncbi.nlm.nih.gov/pubmed/28409823
http://dx.doi.org/10.1111/bph.13820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466536/
https://www.ncbi.nlm.nih.gov/pubmed/28409823
http://dx.doi.org/10.1111/bph.13820

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