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The novel nitric oxide donor PDNO attenuates ovine ischemia-reperfusion induced renal failure
BACKGROUND: Renal ischemia-reperfusion injury is a common cause of acute kidney injury in intensive care and surgery. Recently, novel organic mononitrites of 1,2-propanediol (PDNO) were synthesized and shown to rapidly and controllably deploy nitric oxide in the circulation when administered intrave...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466578/ https://www.ncbi.nlm.nih.gov/pubmed/28600797 http://dx.doi.org/10.1186/s40635-017-0143-4 |