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The novel nitric oxide donor PDNO attenuates ovine ischemia-reperfusion induced renal failure

BACKGROUND: Renal ischemia-reperfusion injury is a common cause of acute kidney injury in intensive care and surgery. Recently, novel organic mononitrites of 1,2-propanediol (PDNO) were synthesized and shown to rapidly and controllably deploy nitric oxide in the circulation when administered intrave...

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Detalles Bibliográficos
Autores principales: Nilsson, Kristofer F., Sandin, John, Gustafsson, Lars E., Frithiof, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466578/
https://www.ncbi.nlm.nih.gov/pubmed/28600797
http://dx.doi.org/10.1186/s40635-017-0143-4