Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch

The Krüppel-like factor (KLF) family of transcription factors play critical roles in haematopoiesis. KLF1, the founding member of the family, has been implicated in the control of both erythropoiesis and megakaryopoiesis. Here we describe a novel system using an artificial dominant negative isoform...

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Detalles Bibliográficos
Autores principales: Norton, Laura J., Hallal, Samantha, Stout, Elizabeth S., Funnell, Alister P. W., Pearson, Richard C. M., Crossley, Merlin, Quinlan, Kate G. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466599/
https://www.ncbi.nlm.nih.gov/pubmed/28600522
http://dx.doi.org/10.1038/s41598-017-03289-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466599/
https://www.ncbi.nlm.nih.gov/pubmed/28600522
http://dx.doi.org/10.1038/s41598-017-03289-5

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