Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway

The RAS signaling pathway is hyperactive in malignant glioma due to overexpression and/or increased activity. A previous study identified that RASD1, a member of the RAS superfamily of small G-proteins, is a significantly dysregulated gene in oligodendroglial tumors that responded to chemotherapy. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Shangfeng, Jin, Lei, Liu, Guangping, Wang, Peng, Sun, Zonghan, Cao, Yujia, Shi, Hengliang, Liu, Xuejiao, Shi, Qiong, Zhou, Xiuping, Yu, Rutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466601/
https://www.ncbi.nlm.nih.gov/pubmed/28600528
http://dx.doi.org/10.1038/s41598-017-03612-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466601/
https://www.ncbi.nlm.nih.gov/pubmed/28600528
http://dx.doi.org/10.1038/s41598-017-03612-0

Ejemplares similares