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Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway
The RAS signaling pathway is hyperactive in malignant glioma due to overexpression and/or increased activity. A previous study identified that RASD1, a member of the RAS superfamily of small G-proteins, is a significantly dysregulated gene in oligodendroglial tumors that responded to chemotherapy. H...
Autores principales: | Gao, Shangfeng, Jin, Lei, Liu, Guangping, Wang, Peng, Sun, Zonghan, Cao, Yujia, Shi, Hengliang, Liu, Xuejiao, Shi, Qiong, Zhou, Xiuping, Yu, Rutong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466601/ https://www.ncbi.nlm.nih.gov/pubmed/28600528 http://dx.doi.org/10.1038/s41598-017-03612-0 |
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