Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe

Intestinal bacterial β-glucuronidase (βG) hydrolyzes glucuronidated metabolites to their toxic form in intestines, resulting in intestinal damage. The development of a method to inhibit βG is thus important but has been limited by the difficulty of directly assessing enzyme activity in live animals....

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Detalles Bibliográficos
Autores principales: Chen, Michael, Cheng, Kai-Wen, Chen, Yi-Jou, Wang, Chang-Hung, Cheng, Ta-Chun, Chang, Kuo-Chien, Kao, An-Pei, Chuang, Kuo-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466677/
https://www.ncbi.nlm.nih.gov/pubmed/28600512
http://dx.doi.org/10.1038/s41598-017-03252-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466677/
https://www.ncbi.nlm.nih.gov/pubmed/28600512
http://dx.doi.org/10.1038/s41598-017-03252-4

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