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Development and Evaluation of (18)F-IRS for Molecular Imaging Mutant EGF Receptors in NSCLC

To prepare and evaluate a new radiotracer (18)F-IRS for molecular imaging mutant EGF Receptors in vitro and vivo. Uptake and efflux of (18)F-IRS were performed with four NSCLC cell lines including HCC827, H1975, H358 and H520. In vivo tumor targeting and pharmacokinetics of the radiotracers were als...

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Detalles Bibliográficos
Autores principales: Song, Yan, Xiao, Zunyu, Wang, Kai, Wang, Xiance, Zhang, Chongqing, Fang, Fang, Sun, Xilin, Shen, Baozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466683/
https://www.ncbi.nlm.nih.gov/pubmed/28600491
http://dx.doi.org/10.1038/s41598-017-01443-7