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Development and Evaluation of (18)F-IRS for Molecular Imaging Mutant EGF Receptors in NSCLC
To prepare and evaluate a new radiotracer (18)F-IRS for molecular imaging mutant EGF Receptors in vitro and vivo. Uptake and efflux of (18)F-IRS were performed with four NSCLC cell lines including HCC827, H1975, H358 and H520. In vivo tumor targeting and pharmacokinetics of the radiotracers were als...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466683/ https://www.ncbi.nlm.nih.gov/pubmed/28600491 http://dx.doi.org/10.1038/s41598-017-01443-7 |