Identification of nocamycin biosynthetic gene cluster from Saccharothrix syringae NRRL B-16468 and generation of new nocamycin derivatives by manipulating gene cluster

BACKGROUND: Nocamycins I and II, produced by the rare actinomycete Saccharothrix syringae, belong to the tetramic acid family natural products. Nocamycins show potent antimicrobial activity and they hold great potential for antibacterial agent design. However, up to now, little is known about the ex...

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Detalles Bibliográficos
Autores principales: Mo, Xuhua, Shi, Chunrong, Gui, Chun, Zhang, Yanjiao, Ju, Jianhua, Wang, Qingji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466765/
https://www.ncbi.nlm.nih.gov/pubmed/28599654
http://dx.doi.org/10.1186/s12934-017-0718-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466765/
https://www.ncbi.nlm.nih.gov/pubmed/28599654
http://dx.doi.org/10.1186/s12934-017-0718-5

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