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Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In this study,...

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Detalles Bibliográficos
Autores principales: Ngolab, Jennifer, Trinh, Ivy, Rockenstein, Edward, Mante, Michael, Florio, Jazmin, Trejo, Margarita, Masliah, Deborah, Adame, Anthony, Masliah, Eliezer, Rissman, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466770/
https://www.ncbi.nlm.nih.gov/pubmed/28599681
http://dx.doi.org/10.1186/s40478-017-0445-5