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Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In this study,...
Autores principales: | Ngolab, Jennifer, Trinh, Ivy, Rockenstein, Edward, Mante, Michael, Florio, Jazmin, Trejo, Margarita, Masliah, Deborah, Adame, Anthony, Masliah, Eliezer, Rissman, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466770/ https://www.ncbi.nlm.nih.gov/pubmed/28599681 http://dx.doi.org/10.1186/s40478-017-0445-5 |
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