SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes

BACKGROUND: Exposure to heat stress after UVB irradiation induces a reduction of apoptosis, resulting in survival of DNA damaged human keratinocytes. This heat-mediated evasion of apoptosis appears to be mediated by activation of SIRT1 and inactivation of p53 signalling. In this study, we assessed t...

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Detalles Bibliográficos
Autores principales: Calapre, Leslie, Gray, Elin S., Kurdykowski, Sandrine, David, Anthony, Descargues, Pascal, Ziman, Mel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466784/
https://www.ncbi.nlm.nih.gov/pubmed/28601088
http://dx.doi.org/10.1186/s12895-017-0060-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466784/
https://www.ncbi.nlm.nih.gov/pubmed/28601088
http://dx.doi.org/10.1186/s12895-017-0060-y

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