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SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
BACKGROUND: Exposure to heat stress after UVB irradiation induces a reduction of apoptosis, resulting in survival of DNA damaged human keratinocytes. This heat-mediated evasion of apoptosis appears to be mediated by activation of SIRT1 and inactivation of p53 signalling. In this study, we assessed t...
Autores principales: | Calapre, Leslie, Gray, Elin S., Kurdykowski, Sandrine, David, Anthony, Descargues, Pascal, Ziman, Mel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466784/ https://www.ncbi.nlm.nih.gov/pubmed/28601088 http://dx.doi.org/10.1186/s12895-017-0060-y |
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