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A New Rat Model of Epileptic Spasms Based on Methylazoxymethanol-Induced Malformations of Cortical Development

Malformations of cortical development (MCDs) can cause medically intractable epilepsies and cognitive disabilities in children. We developed a new model of MCD-associated epileptic spasms by treating rats prenatally with methylazoxymethanol acetate (MAM) to induce cortical malformations and postnata...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Hee, Yum, Mi-Sun, Lee, Minyoung, Kim, Eun-Jin, Shim, Woo-Hyun, Ko, Tae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466970/
https://www.ncbi.nlm.nih.gov/pubmed/28659857
http://dx.doi.org/10.3389/fneur.2017.00271