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A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in children. Despite intensive research in recent decades the prognosis for patients with metastatic or relapsed diseases has hardly improved. New therapeutic concepts in anti-tumor therapy aim to modulate the patient’s immune system t...

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Detalles Bibliográficos
Autores principales: Wagner, Juliane, Pfannenstiel, Viktoria, Waldmann, Anja, Bergs, Judith W. J., Brill, Boris, Huenecke, Sabine, Klingebiel, Thomas, Rödel, Franz, Buchholz, Christian J., Wels, Winfried S., Bader, Peter, Ullrich, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466991/
https://www.ncbi.nlm.nih.gov/pubmed/28659917
http://dx.doi.org/10.3389/fimmu.2017.00676