Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53

Chronic inflammation (CI) is a risk factor for pancreatic cancer (PC) including the most common type, ductal adenocarcinoma (PDAC), but its role and the mechanisms involved are unclear. To investigate the role of CI in PC, we generated genetic mouse models with pancreatic specific CI in the presence...

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Detalles Bibliográficos
Autores principales: Swidnicka-Siergiejko, A K, Gomez-Chou, S B, Cruz-Monserrate, Z, Deng, D, Liu, Y, Huang, H, Ji, B, Azizian, N, Daniluk, J, Lu, W, Wang, H, Maitra, A, Logsdon, C D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467016/
https://www.ncbi.nlm.nih.gov/pubmed/27991926
http://dx.doi.org/10.1038/onc.2016.461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467016/
https://www.ncbi.nlm.nih.gov/pubmed/27991926
http://dx.doi.org/10.1038/onc.2016.461

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