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Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53
Chronic inflammation (CI) is a risk factor for pancreatic cancer (PC) including the most common type, ductal adenocarcinoma (PDAC), but its role and the mechanisms involved are unclear. To investigate the role of CI in PC, we generated genetic mouse models with pancreatic specific CI in the presence...
Autores principales: | Swidnicka-Siergiejko, A K, Gomez-Chou, S B, Cruz-Monserrate, Z, Deng, D, Liu, Y, Huang, H, Ji, B, Azizian, N, Daniluk, J, Lu, W, Wang, H, Maitra, A, Logsdon, C D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467016/ https://www.ncbi.nlm.nih.gov/pubmed/27991926 http://dx.doi.org/10.1038/onc.2016.461 |
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