WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

Aberrant regulation of WNT/β-catenin signaling has a crucial role in the onset and progression of cancers, where the effects are not always predictable depending on tumor context. In melanoma, for example, models of the disease predict differing effects of the WNT/β-catenin pathway on metastatic pro...

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Detalles Bibliográficos
Autores principales: Brown, K, Yang, P, Salvador, D, Kulikauskas, R, Ruohola-Baker, H, Robitaille, A M, Chien, A J, Moon, R T, Sherwood, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467017/
https://www.ncbi.nlm.nih.gov/pubmed/28092677
http://dx.doi.org/10.1038/onc.2016.450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467017/
https://www.ncbi.nlm.nih.gov/pubmed/28092677
http://dx.doi.org/10.1038/onc.2016.450

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