Cargando…

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

Aberrant regulation of WNT/β-catenin signaling has a crucial role in the onset and progression of cancers, where the effects are not always predictable depending on tumor context. In melanoma, for example, models of the disease predict differing effects of the WNT/β-catenin pathway on metastatic pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brown, K, Yang, P, Salvador, D, Kulikauskas, R, Ruohola-Baker, H, Robitaille, A M, Chien, A J, Moon, R T, Sherwood, V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467017/ https://www.ncbi.nlm.nih.gov/pubmed/28092677 http://dx.doi.org/10.1038/onc.2016.450

Ejemplares similares

Activation of Wnt/β-Catenin Signaling Increases Apoptosis in Melanoma Cells Treated with Trail
por: Zimmerman, Zachary F., et al.
Publicado: (2013)

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers
por: Lucero, Olivia M., et al.
Publicado: (2010)

Targeted BRAF Inhibition Impacts Survival in Melanoma Patients with High Levels of Wnt/β-Catenin Signaling
por: Chien, Andy J., et al.
Publicado: (2014)

Protein Kinase PKN1 Represses Wnt/β-Catenin Signaling in Human Melanoma Cells
por: James, Richard G., et al.
Publicado: (2013)

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
por: Arensman, Michael D., et al.
Publicado: (2013)

Differential Activation of Wnt-β-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner
por: Dey, Nandini, et al.
Publicado: (2013)

Loss of autophagy affects melanoma development in a manner dependent on PTEN status
por: Rosenfeldt, Mathias T., et al.
Publicado: (2021)

Ligustrazine eases lung cancer by regulating PTEN and Wnt/β-catenin pathway
por: Dong, Yuehua, et al.
Publicado: (2020)

PORCN promotes hepatocellular carcinogenesis via Wnt/β-catenin-dependent manner
por: Wu, Shuzhen, et al.
Publicado: (2023)

Hyperphosphorylated PTEN exerts oncogenic properties
por: van Ree, Janine H., et al.
Publicado: (2023)

Wnt/β-catenin, an oncogenic pathway targeted by H. pylori in gastric carcinogenesis
por: Song, Xiaowen, et al.
Publicado: (2015)

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells
por: Conrad, Willliam, et al.
Publicado: (2013)

WNT10A Plays an Oncogenic Role in Renal Cell Carcinoma by Activating WNT/β-catenin Pathway
por: Hsu, Ren-Jun, et al.
Publicado: (2012)

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β-catenin signaling
por: Li, Jinlong, et al.
Publicado: (2019)

Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer
por: Cheltsov, Anton, et al.
Publicado: (2020)

Nuclear S6K1 Enhances Oncogenic Wnt Signaling by Inducing Wnt/β-Catenin Transcriptional Complex Formation
por: Lee, Min Gyu, et al.
Publicado: (2022)

Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma
por: Trujillo, Jonathan A., et al.
Publicado: (2019)

Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin
por: Erazo-Oliveras, Alfredo, et al.
Publicado: (2023)

SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ß-catenin signaling
por: Prévostel, Corinne, et al.
Publicado: (2016)

Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner
por: Rharass, Tareck, et al.
Publicado: (2017)

Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency
por: Mathieu, J., et al.
Publicado: (2019)

RTL1 promotes melanoma proliferation by regulating Wnt/β-catenin signalling
por: Fan, Guobiao, et al.
Publicado: (2017)

Global Regulator SATB1 Recruits β-Catenin and Regulates T(H)2 Differentiation in Wnt-Dependent Manner
por: Notani, Dimple, et al.
Publicado: (2010)

Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner
por: Su, Zijie, et al.
Publicado: (2018)

The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner
por: Wiese, Maria, et al.
Publicado: (2017)

Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN
por: Tanwar, Pradeep S., et al.
Publicado: (2011)

PTEN suppresses the inflammation, viability, and motility of AP-AR42J cells by activating the Wnt/β-catenin pathway
por: Yan, Hongtao, et al.
Publicado: (2019)

Targeting Oncogenic Wnt/β-Catenin Signaling in Adrenocortical Carcinoma Disrupts ECM Expression and Impairs Tumor Growth
por: Penny, Morgan K., et al.
Publicado: (2023)

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer
por: Lemieux, E, et al.
Publicado: (2015)

Comparison of gene expression of the oncogenic Wnt/β-catenin signaling pathway components in the mouse and human epididymis
por: Wang, Kai, et al.
Publicado: (2015)

Coronin 3 Promotes the Development of Oncogenic Properties in Glioma Through the Wnt/β-Catenin Signaling Pathway
por: Wang, Min, et al.
Publicado: (2020)

Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells
por: Kalra, Hina, et al.
Publicado: (2019)

Oncogenic UBE3C promotes breast cancer progression by activating Wnt/β-catenin signaling
por: Hang, Chen, et al.
Publicado: (2021)

Retraction: TRIM22 functions as an oncogene in gliomas through regulating the Wnt/β-catenin signaling pathway
por: Fisher, Laura
Publicado: (2021)

Role of the Wnt-β-catenin signaling pathway in melanoma-mediated dendritic cell tolerization
por: Holtzhausen, Alisha, et al.
Publicado: (2013)

Nomogram Incorporating the WNT/β-Catenin Signaling Pathway for Predicting the Survival of Cutaneous Melanoma
por: Zhou, Yu-Xin, et al.
Publicado: (2021)

Using Mitochondrial Trifunctional Protein Deficiency to Understand Maternal Health
por: Miklas, Jason W., et al.
Publicado: (2020)

Oncogenic Serine 45-Deleted β-Catenin Remains Susceptible to Wnt Stimulation and APC Regulation in Human Colonocytes
por: Parker, Taybor W., et al.
Publicado: (2020)

CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma
por: Feng, Fan, et al.
Publicado: (2021)

Retracted Article: TRIM22 functions as an oncogene in gliomas through regulating the Wnt/β-catenin signaling pathway
por: Tang, Shi-lei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l16ebvqberd201kge0nfgu84i5