Inhibitory effect of oxymatrine on hepatocyte apoptosis via TLR4/PI3K/Akt/GSK-3β signaling pathway

AIM: To evaluate the effect of oxymatrine (OMT) on hepatocyte apoptosis in rats with lipopolysaccharide (LPS)/D-galactosamine (D-GalN)-induced acute liver failure (ALF). METHODS: LPS/D-GalN was used to establish a model of ALF in rats. To evaluate the effect of OMT, we assessed apoptosis by transmis...

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Detalles Bibliográficos
Autores principales: Zhang, Xian, Jiang, Wei, Zhou, Ai-Ling, Zhao, Min, Jiang, Dao-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467070/
https://www.ncbi.nlm.nih.gov/pubmed/28638224
http://dx.doi.org/10.3748/wjg.v23.i21.3839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467070/
https://www.ncbi.nlm.nih.gov/pubmed/28638224
http://dx.doi.org/10.3748/wjg.v23.i21.3839

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