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Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in Yeast

Ribosome profiling quantitatively captures ribosome locations during translation. The resulting profiles of ribosome locations are widely used to study translational speed. However, an accurate estimation of the ribosome location depends on identifying the A-site from ribosome profiling reads, a pro...

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Detalles Bibliográficos
Autores principales: Wang, Hao, McManus, Joel, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467134/
https://www.ncbi.nlm.nih.gov/pubmed/27726445
http://dx.doi.org/10.1089/cmb.2016.0147