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A molecular portrait of microsatellite instability across multiple cancers

Microsatellite instability (MSI) refers to the hypermutability of short repetitive sequences in the genome caused by impaired DNA mismatch repair. Although MSI has been studied for decades, large amounts of sequencing data now available allows us to examine the molecular fingerprints of MSI in great...

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Detalles Bibliográficos
Autores principales: Cortes-Ciriano, Isidro, Lee, Sejoon, Park, Woong-Yang, Kim, Tae-Min, Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467167/
https://www.ncbi.nlm.nih.gov/pubmed/28585546
http://dx.doi.org/10.1038/ncomms15180