Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues

[Image: see text] A synthesis strategy for the swift generation of 4″-modified α-galactosylceramide (α-GalCer) analogues is described, establishing a chemical platform to comprehensively investigate the structure–activity relationships (SAR) of this understudied glycolipid part. The strategy relies...

Descripción completa

Detalles Bibliográficos
Autores principales: Janssens, Jonas, Decruy, Tine, Venken, Koen, Seki, Toshiyuki, Krols, Simon, Van der Eycken, Johan, Tsuji, Moriya, Elewaut, Dirk, Van Calenbergh, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467197/
https://www.ncbi.nlm.nih.gov/pubmed/28626526
http://dx.doi.org/10.1021/acsmedchemlett.7b00107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467197/
https://www.ncbi.nlm.nih.gov/pubmed/28626526
http://dx.doi.org/10.1021/acsmedchemlett.7b00107

Ejemplares similares