Mechanism of microtubule stabilization by taccalonolide AJ

As a major component of the cytoskeleton, microtubules consist of αβ-tubulin heterodimers and have been recognized as attractive targets for cancer chemotherapy. Microtubule-stabilizing agents (MSAs) promote polymerization of tubulin and stabilize the polymer, preventing depolymerization. The molecu...

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Detalles Bibliográficos
Autores principales: Wang, Yuxi, Yu, Yamei, Li, Guo-Bo, Li, Shu-Ang, Wu, Chengyong, Gigant, Benoît, Qin, Wenming, Chen, Hao, Wu, Yangping, Chen, Qiang, Yang, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467209/
https://www.ncbi.nlm.nih.gov/pubmed/28585532
http://dx.doi.org/10.1038/ncomms15787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467209/
https://www.ncbi.nlm.nih.gov/pubmed/28585532
http://dx.doi.org/10.1038/ncomms15787

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