IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours

During cancer immunoediting, loss of major histocompatibility complex class I (MHC-I) in neoplasm contributes to the evasion of tumours from host immune system. Recent studies have demonstrated that most natural killer (NK) cells that are found in advanced cancers are defective, releasing the malign...

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Detalles Bibliográficos
Autores principales: Seo, Hyungseok, Jeon, Insu, Kim, Byung-Seok, Park, Myunghwan, Bae, Eun-Ah, Song, Boyeong, Koh, Choong-Hyun, Shin, Kwang-Soo, Kim, Il-Kyu, Choi, Kiyoung, Oh, Taegwon, Min, Jiyoun, Min, Byung Soh, Han, Yoon Dae, Kang, Suk-Jo, Shin, Sang Joon, Chung, Yeonseok, Kang, Chang-Yuil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467212/
https://www.ncbi.nlm.nih.gov/pubmed/28585539
http://dx.doi.org/10.1038/ncomms15776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467212/
https://www.ncbi.nlm.nih.gov/pubmed/28585539
http://dx.doi.org/10.1038/ncomms15776

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