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Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment

Major depressive disorder (MDD) affects millions of patients; however, the pathophysiology is poorly understood. Rodent models have been developed using chronic mild stress or unavoidable punishment (learned helplessness) to induce features of depression, like general inactivity and anhedonia. Here...

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Detalles Bibliográficos
Autores principales: Ries, Ariane-Saskia, Hermanns, Tim, Poeck, Burkhard, Strauss, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467214/
https://www.ncbi.nlm.nih.gov/pubmed/28585544
http://dx.doi.org/10.1038/ncomms15738