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Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

Cellular senescence prevents the proliferation of cells at risk for neoplastic transformation. However, the altered secretome of senescent cells can promote the growth of the surrounding cancer cells. Although extracellular vesicles (EVs) have emerged as new players in intercellular communication, t...

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Detalles Bibliográficos
Autores principales: Takasugi, Masaki, Okada, Ryo, Takahashi, Akiko, Virya Chen, David, Watanabe, Sugiko, Hara, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467215/
https://www.ncbi.nlm.nih.gov/pubmed/28585531
http://dx.doi.org/10.1038/ncomms15728