Crystal structures of U6 snRNA-specific terminal uridylyltransferase

The terminal uridylyltransferase, TUT1, builds or repairs the 3′-oligo-uridylylated tail of U6 snRNA. The 3′-oligo-uridylylated tail is the Lsm-binding site for U4/U6 di-snRNP formation and U6 snRNA recycling for pre-mRNA splicing. Here, we report crystallographic and biochemical analyses of human T...

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Detalles Bibliográficos
Autores principales: Yamashita, Seisuke, Takagi, Yuko, Nagaike, Takashi, Tomita, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467268/
https://www.ncbi.nlm.nih.gov/pubmed/28589955
http://dx.doi.org/10.1038/ncomms15788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467268/
https://www.ncbi.nlm.nih.gov/pubmed/28589955
http://dx.doi.org/10.1038/ncomms15788

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