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Crystal structures of U6 snRNA-specific terminal uridylyltransferase
The terminal uridylyltransferase, TUT1, builds or repairs the 3′-oligo-uridylylated tail of U6 snRNA. The 3′-oligo-uridylylated tail is the Lsm-binding site for U4/U6 di-snRNP formation and U6 snRNA recycling for pre-mRNA splicing. Here, we report crystallographic and biochemical analyses of human T...
Autores principales: | Yamashita, Seisuke, Takagi, Yuko, Nagaike, Takashi, Tomita, Kozo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467268/ https://www.ncbi.nlm.nih.gov/pubmed/28589955 http://dx.doi.org/10.1038/ncomms15788 |
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