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Homocysteine Induces Apoptosis of Human Umbilical Vein Endothelial Cells via Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

Homocysteine- (Hcy-) induced endothelial cell apoptosis has been suggested as a cause of Hcy-dependent vascular injury, while the proposed molecular pathways underlying this process are unclear. In this study, we investigated the adverse effects of Hcy on human umbilical vein endothelial cells (HUVE...

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Detalles Bibliográficos
Autores principales: Zhang, Zhimin, Wei, Congying, Zhou, Yanfen, Yan, Tao, Wang, Zhengqiang, Li, Wei, Zhao, Lianyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467318/
https://www.ncbi.nlm.nih.gov/pubmed/28630659
http://dx.doi.org/10.1155/2017/5736506