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Homocysteine Induces Apoptosis of Human Umbilical Vein Endothelial Cells via Mitochondrial Dysfunction and Endoplasmic Reticulum Stress
Homocysteine- (Hcy-) induced endothelial cell apoptosis has been suggested as a cause of Hcy-dependent vascular injury, while the proposed molecular pathways underlying this process are unclear. In this study, we investigated the adverse effects of Hcy on human umbilical vein endothelial cells (HUVE...
Autores principales: | Zhang, Zhimin, Wei, Congying, Zhou, Yanfen, Yan, Tao, Wang, Zhengqiang, Li, Wei, Zhao, Lianyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467318/ https://www.ncbi.nlm.nih.gov/pubmed/28630659 http://dx.doi.org/10.1155/2017/5736506 |
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