Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration

Sirtuins are highly conserved lysine deacetylases involved in ageing, energy production, and lifespan extension. The mammalian SIRT2 has been implicated in Parkinson's disease (PD) where studies suggest SIRT2 promotes neurodegeneration. We therefore evaluated the effects of SIRT2 manipulation i...

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Detalles Bibliográficos
Autores principales: Singh, Preeti, Hanson, Peter S., Morris, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467326/
https://www.ncbi.nlm.nih.gov/pubmed/28634568
http://dx.doi.org/10.1155/2017/2643587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467326/
https://www.ncbi.nlm.nih.gov/pubmed/28634568
http://dx.doi.org/10.1155/2017/2643587

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