Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB

BACKGROUND: LBP and fractalkine are known to be involved in the pathogenesis of ARDS. This study investigated the relationship between LBP and fractalkine in LPS-induced A549 cells and rat lung tissue in an ARDS rat model. METHODS: A549 cells were transfected with LBP or LBP shRNA plasmid DNA or pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xia, Zeng, Yi, Jiang, Yujie, Qin, Yueqiu, Luo, Weigui, Xiang, Shulin, Sooranna, Suren R., Pinhu, Liao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467387/
https://www.ncbi.nlm.nih.gov/pubmed/28634422
http://dx.doi.org/10.1155/2017/9734837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467387/
https://www.ncbi.nlm.nih.gov/pubmed/28634422
http://dx.doi.org/10.1155/2017/9734837

Ejemplares similares