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Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB

BACKGROUND: LBP and fractalkine are known to be involved in the pathogenesis of ARDS. This study investigated the relationship between LBP and fractalkine in LPS-induced A549 cells and rat lung tissue in an ARDS rat model. METHODS: A549 cells were transfected with LBP or LBP shRNA plasmid DNA or pre...

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Detalles Bibliográficos
Autores principales:	Huang, Xia, Zeng, Yi, Jiang, Yujie, Qin, Yueqiu, Luo, Weigui, Xiang, Shulin, Sooranna, Suren R., Pinhu, Liao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467387/ https://www.ncbi.nlm.nih.gov/pubmed/28634422 http://dx.doi.org/10.1155/2017/9734837

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