DIMP53‐1: a novel small‐molecule dual inhibitor of p53–MDM2/X interactions with multifunctional p53‐dependent anticancer properties

The transcription factor p53 plays a crucial role in cancer development and dissemination, and thus, p53‐targeted therapies are among the most encouraging anticancer strategies. In human cancers with wild‐type (wt) p53, its inactivation by interaction with murine double minute (MDM)2 and MDMX is a c...

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Detalles Bibliográficos
Autores principales: Soares, Joana, Espadinha, Margarida, Raimundo, Liliana, Ramos, Helena, Gomes, Ana Sara, Gomes, Sara, Loureiro, Joana B., Inga, Alberto, Reis, Flávio, Gomes, Célia, Santos, Maria M. M., Saraiva, Lucília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467495/
https://www.ncbi.nlm.nih.gov/pubmed/28296148
http://dx.doi.org/10.1002/1878-0261.12051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467495/
https://www.ncbi.nlm.nih.gov/pubmed/28296148
http://dx.doi.org/10.1002/1878-0261.12051

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