Heat‐shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF

The small heat‐shock protein of 27 kDa (HSP27) is highly expressed in many cancers and is associated with aggressive tumour behaviour, metastasis, poor prognosis and resistance to chemotherapy. We aimed at assessing the role of HSP27 in modulating responses to target therapies. We selected several o...

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Detalles Bibliográficos
Autores principales: Konda, John D., Olivero, Martina, Musiani, Daniele, Lamba, Simona, Di Renzo, Maria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467498/
https://www.ncbi.nlm.nih.gov/pubmed/28182330
http://dx.doi.org/10.1002/1878-0261.12042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467498/
https://www.ncbi.nlm.nih.gov/pubmed/28182330
http://dx.doi.org/10.1002/1878-0261.12042

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