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Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish

Hypoxia is an important environmental stressor leading to endocrine disruption and reproductive impairment in fish. Although the hypoxia-inducible factor 1 (HIF-1) is known to regulate the transcription of various genes mediating oxygen homeostasis, its role in modulating steroidogenesis-related gen...

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Detalles Bibliográficos
Autores principales: Tan, Tianfeng, Yu, Richard Man Kit, Wu, Rudolf Shiu Sun, Kong, Richard Yuen Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467919/
https://www.ncbi.nlm.nih.gov/pubmed/28634424
http://dx.doi.org/10.1177/1177625017713193